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Antikörper

FKBP1A/B rabbit pAb

Produktgrößen
50UL
£ POA
ES16393-50UL
100UL
£ POA
ES16393-100UL
Über dieses Produkt
SKU:
ES16393
Anwendung:
Immunohistochemistry, Immunofluorescence, Western Blot
Klonalität:
Polyclonal
Konzentration:
1 mg/ml
Weitere Details:
The protein encoded by this gene is a member of the immunophilin protein family; which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels; and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor. In mouse; deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium. Multiple alternatively spliced variants; encoding the same protein; have been identified. The human genome contains five pseudogenes related to this gene; at least one of which is transcribed. [provided b
Immunogen:
Synthesized peptide derived from human FKBP1A/B AA range: 26-75
Isotyp:
IgG
Reaktivitäten:
Human, Mouse, Rat
Versandbedingungen:
Blue Ice
Quelle:
Rabbit
Lagerbedingungen:
-20[o]C
Hersteller:
ELK Biotechnology
Typ:
Antibodies: Polyclonal Antibody
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