AIF-M1 rabbit pAb
Produktgrößen
50UL
£ POA
ES1615-50UL
100UL
£ POA
ES1615-100UL
Über dieses Produkt
- SKU:
- ES1615
- Zusätzliche Namen:
- AIFM1; AIF; PDCD8; Apoptosis-inducing factor 1; mitochondrial; Programmed cell death protein 8
- Anwendung:
- Western Blot, Immunohistochemistry, Immunofluorescence, ELISA
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells; and it is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it affects chromosome condensation and fragmentation. In addition; this gene product induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. Mutations in this gene cause combined oxidative phosphorylation deficiency 6 (COXPD6); a severe mitochondrial encephalomyopathy; as well as Cowchock syndrome; also known as X-linked recessive Charcot-Marie-Tooth disease-4 (CMTX-4); a disorder resulting in neuropathy; and axonal and motor-sensory defects with deafness and mental retardation. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human AIFM1. AA range:51-100
- Isotyp:
- IgG
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Quelle:
- Rabbit
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- ELK Biotechnology
- Typ:
- Antibodies: Polyclonal Antibody
