GPX2 rabbit pAb
Produktgrößen
50UL
£ POA
ES15920-50UL
100UL
£ POA
ES15920-100UL
Über dieses Produkt
- SKU:
- ES15920
- Anwendung:
- Western Blot
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- The protein encoded by this gene belongs to the glutathione peroxidase family; members of which catalyze the reduction of organic hydroperoxides and hydrogen peroxide (H2O2) by glutathione; and thereby protect cells against oxidative damage. Several isozymes of this gene family exist in vertebrates; which vary in cellular location and substrate specificity. This isozyme is predominantly expressed in the gastrointestinal tract (also in liver in human); is localized in the cytoplasm; and whose preferred substrate is hydrogen peroxide. Overexpression of this gene is associated with increased differentiation and proliferation in colorectal cancer. This isozyme is also a selenoprotein; containing the rare amino acid selenocysteine (Sec) at its active site. Sec is encoded by the UGA codon; which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure; designated the Sec insertion sequence (SECIS) element; that is necessary for the recognition of UGA as a Sec codon; rather than as a stop signal. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq; Jul 2016];
- Immunogen:
- Synthesized peptide derived from human GPX2 AA range: 113-163
- Isotyp:
- IgG
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Quelle:
- Rabbit
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- ELK Biotechnology
- Typ:
- Antibodies: Polyclonal Antibody
