GSTM3 rabbit pAb
Produktgrößen
50UL
£ POA
ES15872-50UL
100UL
£ POA
ES15872-100UL
Über dieses Produkt
- SKU:
- ES15872
- Anwendung:
- Western Blot
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present; eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha; kappa; mu; omega; pi; sigma; theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds; including carcinogens; therapeutic drugs; environmental toxins and products of oxidative stress; by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Mutations of this class mu gene have been linked with a slight increase in a number of cancers; likely due to exposure with environmental toxins. Alternative splicing results in multiple transcript variants. [provided by RefSeq; Nov 2008];
- Immunogen:
- Synthesized peptide derived from human GSTM3 AA range: 1-51
- Isotyp:
- IgG
- Reaktivitäten:
- Human, Rat, Mouse
- Versandbedingungen:
- Blue Ice
- Quelle:
- Rabbit
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- ELK Biotechnology
- Typ:
- Antibodies: Polyclonal Antibody
