Met (phospho-Tyr1234/1235) rabbit pAb
Produktgrößen
50UL
£ POA
ES14967-50UL
100UL
£ POA
ES14967-100UL
Über dieses Produkt
- SKU:
- ES14967
- Zusätzliche Namen:
- Hepatocyte growth factor receptor (HGF receptor) (EC 2.7.10.1) (HGF/SF receptor) (Proto-oncogene c-Met) (Scatter factor receptor) (SF receptor) (Tyrosine-protein kinase Met)
- Anwendung:
- Western Blot, ELISA, Immunohistochemistry
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that are linked via disulfide bonds to form the mature receptor. Further processing of the beta subunit results in the formation of the M10 peptide; which has been shown to reduce lung fibrosis. Binding of its ligand; hepatocyte growth factor; induces dimerization and activation of the receptor; which plays a role in cellular survival; embryogenesis; and cellular migration and invasion. Mutations in this gene are associated with papillary renal cell carcinoma; hepatocellular carcinoma; and various head and neck cancers. Amplification and overexpression of this gene are also associated with multiple human cancers. [provided by RefSeq; May 2016];
- Immunogen:
- Synthesized phosho peptide around human Met (Tyr1234 and 1235)
- Isotyp:
- IgG
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Quelle:
- Rabbit
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- ELK Biotechnology
- Typ:
- Antibodies: Polyclonal Antibody
