MLKL (phospho Ser358) rabbit pAb
Produktgrößen
50UL
£ POA
ES14935-50UL
100UL
£ POA
ES14935-100UL
Über dieses Produkt
- SKU:
- ES14935
- Zusätzliche Namen:
- Mixed lineage kinase domain-like protein
- Anwendung:
- Immunohistochemistry, Immunofluorescence, Western Blot
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- This gene belongs to the protein kinase superfamily. The encoded protein contains a protein kinase-like domain; however; is thought to be inactive because it lacks several residues required for activity. This protein plays a critical role in tumor necrosis factor (TNF)-induced necroptosis; a programmed cell death process; via interaction with receptor-interacting protein 3 (RIP3); which is a key signaling molecule in necroptosis pathway. Inhibitor studies and knockdown of this gene inhibited TNF-induced necrosis. High levels of this protein and RIP3 are associated with inflammatory bowel disease in children. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq; Sep 2015];
- Immunogen:
- Synthesized peptide derived from human MLKL (phospho S358)
- Isotyp:
- IgG
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Quelle:
- Rabbit
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- ELK Biotechnology
- Typ:
- Antibodies: Polyclonal Antibody
