Stat2 (phospho Tyr690) rabbit pAb
Produktgrößen
50UL
£ POA
ES1478-50UL
100UL
£ POA
ES1478-100UL
Über dieses Produkt
- SKU:
- ES1478
- Zusätzliche Namen:
- STAT2; Signal transducer and activator of transcription 2; p113
- Anwendung:
- Western Blot, Immunohistochemistry, Immunofluorescence, ELISA
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors; STAT family members are phosphorylated by the receptor associated kinases; and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN); this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G); in which this protein acts as a transactivator; but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein; which is thought to be involved in the process of blocking IFN-alpha response by adenovirus. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq; Mar 2010];
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human STAT2 around the phosphorylation site of Tyr690. AA range:656-705
- Isotyp:
- IgG
- Reaktivitäten:
- Human, Rat
- Versandbedingungen:
- Blue Ice
- Quelle:
- Rabbit
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- ELK Biotechnology
- Typ:
- Antibodies: Polyclonal Antibody
