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Antikörper

NOD1 rabbit pAb

Produktgrößen
50UL
£ POA
ES14472-50UL
100UL
£ POA
ES14472-100UL
Über dieses Produkt
SKU:
ES14472
Zusätzliche Namen:
Nucleotide-binding oligomerization domain-containing protein 1 (Caspase recruitment domain-containing protein 4)
Anwendung:
Western Blot
Klonalität:
Polyclonal
Konzentration:
1 mg/ml
Weitere Details:
This gene encodes a member of the NOD (nucleotide-binding oligomerization domain) family. This member is a cytosolic protein. It contains an N-terminal caspase recruitment domain (CARD); a centrally located nucleotide-binding domain (NBD); and 10 tandem leucine-rich repeats (LRRs) in its C terminus. The CARD is involved in apoptotic signaling; LRRs participate in protein-protein interactions; and mutations in the NBD may affect the process of oligomerization and subsequent function of the LRR domain. This protein is an intracellular pattern-recognition receptor (PRR) that initiates inflammation in response to a subset of bacteria through the detection of bacterial diaminopimelic acid. Multiple alternatively spliced transcript variants differring in the 5' UTR have been described; but the full-length nature of these variants has not been determined. [provided by RefSeq; Oct 2009];
Immunogen:
Synthesized peptide derived from human NOD1 AA range: 290-340
Isotyp:
IgG
Reaktivitäten:
Human, Mouse
Versandbedingungen:
Blue Ice
Quelle:
Rabbit
Lagerbedingungen:
-20[o]C
Hersteller:
ELK Biotechnology
Typ:
Antibodies: Polyclonal Antibody
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