p38 (phospho Thr180/Y182) rabbit pAb
Produktgrößen
50UL
£ POA
ES1431-50UL
100UL
£ POA
ES1431-100UL
Über dieses Produkt
- SKU:
- ES1431
- Zusätzliche Namen:
- MAPK14; CSBP; CSBP1; CSBP2; CSPB1; MXI2; SAPK2A; Mitogen-activated protein kinase 14; MAP kinase 14; MAPK 14; Cytokine suppressive anti-inflammatory drug-binding protein; CSAID-binding protein; CSBP; MAP kinase MXI2; MAX-interacting protein
- Anwendung:
- Immunofluorescence, Western Blot, Immunohistochemistry, ELISA
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals; and are involved in a wide variety of cellular processes such as proliferation; differentiation; transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs); or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2; MEF2C; and MAX; cell cycle regulator CDC25B; and tumor suppressor p53; which suggest the roles of this kinase in stress related transcription and cell cycle regulation; as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding d
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human p38 MAPK around the phosphorylation site of Thr179 and Tyr181. AA range:151-200
- Isotyp:
- IgG
- Reaktivitäten:
- Human, Mouse, Rat, Guinea Pig
- Versandbedingungen:
- Blue Ice
- Quelle:
- Rabbit
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- ELK Biotechnology
- Typ:
- Antibodies: Polyclonal Antibody