p27 (phospho Thr187) rabbit pAb
Produktgrößen
50UL
£ POA
ES1418-50UL
100UL
£ POA
ES1418-100UL
Über dieses Produkt
- SKU:
- ES1418
- Zusätzliche Namen:
- CDKN1B; KIP1; Cyclin-dependent kinase inhibitor 1B; Cyclin-dependent kinase inhibitor p27; p27Kip1
- Anwendung:
- Western Blot, Immunohistochemistry, Immunofluorescence, ELISA
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- This gene encodes a cyclin-dependent kinase inhibitor; which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes; and thus controls the cell cycle progression at G1. The degradation of this protein; which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes; is required for the cellular transition from quiescence to the proliferative state. Mutations in this gene are associated with multiple endocrine neoplasia type IV (MEN4). [provided by RefSeq; Apr 2014];
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human p27 Kip1 around the phosphorylation site of Thr187. AA range:149-198
- Isotyp:
- IgG
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Quelle:
- Rabbit
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- ELK Biotechnology
- Typ:
- Antibodies: Polyclonal Antibody
