Stat6 (phospho Thr645) rabbit pAb
Produktgrößen
50UL
£ POA
ES1408-50UL
100UL
£ POA
ES1408-100UL
Über dieses Produkt
- SKU:
- ES1408
- Zusätzliche Namen:
- STAT6; Signal transducer and activator of transcription 6; IL-4 Stat
- Anwendung:
- Western Blot, Immunohistochemistry, Immunofluorescence, Immunoprecipitation, ELISA
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors; STAT family members are phosphorylated by the receptor associated kinases; and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L); which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells; expression of cell surface markers; and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.[provided by RefSeq; May 2010];
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human STAT6 around the phosphorylation site of Thr645. AA range:612-661
- Isotyp:
- IgG
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Quelle:
- Rabbit
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- ELK Biotechnology
- Typ:
- Antibodies: Polyclonal Antibody
