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Antikörper

HDAC5 (phospho Ser498) rabbit pAb

Produktgrößen
50UL
£ POA
ES1324-50UL
100UL
£ POA
ES1324-100UL
Über dieses Produkt
SKU:
ES1324
Zusätzliche Namen:
HDAC5; KIAA0600; Histone deacetylase 5; HD5; Antigen NY-CO-9
Anwendung:
Western Blot, Immunohistochemistry, Immunofluorescence, ELISA
Klonalität:
Polyclonal
Konzentration:
1 mg/ml
Weitere Details:
Histones play a critical role in transcriptional regulation; cell cycle progression; and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the class II histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins; resulting in repression of MEF2-dependent genes. This gene is thought to be associated with colon cancer. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq; Jul 2008];
Immunogen:
The antiserum was produced against synthesized peptide derived from human HDAC5 around the phosphorylation site of Ser498. AA range:464-513
Isotyp:
IgG
Reaktivitäten:
Human, Mouse
Versandbedingungen:
Blue Ice
Quelle:
Rabbit
Lagerbedingungen:
-20[o]C
Hersteller:
ELK Biotechnology
Typ:
Antibodies: Polyclonal Antibody
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