Shc (phospho-Ser239/240) rabbit pAb
Produktgrößen
50UL
£ POA
ES13126-50UL
100UL
£ POA
ES13126-100UL
Über dieses Produkt
- SKU:
- ES13126
- Zusätzliche Namen:
- SHC-transforming protein 1 (SHC-transforming protein 3) (SHC-transforming protein A) (Src homology 2 domain-containing-transforming protein C1) (SH2 domain protein C1)
- Anwendung:
- Western Blot, ELISA, Immunohistochemistry
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- This gene encodes three main isoforms that differ in activities and subcellular location. While all three are adapter proteins in signal transduction pathways; the longest (p66Shc) may be involved in regulating life span and the effects of reactive oxygen species. The other two isoforms; p52Shc and p46Shc; link activated receptor tyrosine kinases to the Ras pathway by recruitment of the GRB2/SOS complex. p66Shc is not involved in Ras activation. Unlike the other two isoforms; p46Shc is targeted to the mitochondrial matrix. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq; Feb 2011];
- Immunogen:
- Synthesized phosho peptide around human Shc (Ser239 and 240)
- Isotyp:
- IgG
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Quelle:
- Rabbit
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- ELK Biotechnology
- Typ:
- Antibodies: Polyclonal Antibody
