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Antikörper

SPTC3 rabbit pAb

Produktgrößen
50UL
£ POA
ES12971-50UL
100UL
£ POA
ES12971-100UL
Über dieses Produkt
SKU:
ES12971
Anwendung:
Western Blot
Klonalität:
Polyclonal
Konzentration:
1 mg/ml
Weitere Details:
The SPTLC3 gene encodes an isoform of the third subunit of serine palmitoyltransferase (SPT; EC 2.3.1.50); which catalyzes the rate-limiting step of the de novo synthesis of sphingolipids (Hornemann et al.; 2006 [PubMed 17023427]). SPT contains 2 main subunits: the common SPTLC1 subunit (MIM 605712) and either SPTLC2 (MIM 605713) or its isoform SPTLC2L (SPTLC3); depending on the tissue in which biosynthesis occurs (Hornemann et al.; 2006 [PubMed 17023427]). There are also 2 highly related isoforms of a third subunit; SSSPTA (MIM 613540) and SSSPTB (MIM 610412); that confer acyl-CoA preference of the SPT enzyme and are essential for maximal enzyme activity (Han et al.; 2009 [PubMed 19416851]).[supplied by OMIM; Nov 2010];
Immunogen:
Synthesized peptide derived from human SPTC3 AA range: 341-391
Isotyp:
IgG
Reaktivitäten:
Human, Mouse
Versandbedingungen:
Blue Ice
Quelle:
Rabbit
Lagerbedingungen:
-20[o]C
Hersteller:
ELK Biotechnology
Typ:
Antibodies: Polyclonal Antibody
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