Stat5 (phospho-Tyr694) rabbit pAb
Produktgrößen
50UL
£ POA
ES12918-50UL
100UL
£ POA
ES12918-100UL
Über dieses Produkt
- SKU:
- ES12918
- Zusätzliche Namen:
- Signal transducer and activator of transcription 5B
- Anwendung:
- Western Blot, Immunohistochemistry
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors; STAT family members are phosphorylated by the receptor associated kinases; and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands; such as IL2; IL4; CSF1; and different growth hormones. It has been shown to be involved in diverse biological processes; such as TCR signaling; apoptosis; adult mammary gland development; and sexual dimorphism of liver gene expression. This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL). The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL. [provi
- Immunogen:
- Synthesized phosho peptide around human Stat5 (Tyr694)
- Isotyp:
- IgG
- Reaktivitäten:
- Human, Mouse
- Versandbedingungen:
- Blue Ice
- Quelle:
- Rabbit
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- ELK Biotechnology
- Typ:
- Antibodies: Polyclonal Antibody
