TAB2 (phospho-Ser372) rabbit pAb
Produktgrößen
50UL
£ POA
ES12828-50UL
100UL
£ POA
ES12828-100UL
Über dieses Produkt
- SKU:
- ES12828
- Zusätzliche Namen:
- TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 (Mitogen-activated protein kinase kinase kinase 7-interacting protein 2) (TAK1-binding protein 2) (TAB-2) (TGF-beta-activated kinase 1-binding protein 2)
- Anwendung:
- Western Blot
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- The protein encoded by this gene is an activator of MAP3K7/TAK1; which is required for for the IL-1 induced activation of nuclear factor kappaB and MAPK8/JNK. This protein forms a kinase complex with TRAF6; MAP3K7 and TAB1; and it thus serves as an adaptor that links MAP3K7 and TRAF6. This protein; along with TAB1 and MAP3K7; also participates in the signal transduction induced by TNFSF11/RANKl through the activation of the receptor activator of NF-kappaB (TNFRSF11A/RANK); which may regulate the development and function of osteoclasts. Studies of the related mouse protein indicate that it functions to protect against liver damage caused by chemical stressors. Mutations in this gene cause congenital heart defects; multiple types; 2 (CHTD2). Alternative splicing results in multiple transcript variants. [provided by RefSeq; May 2014];
- Immunogen:
- Synthesized phosho peptide around human TAB2 (Ser372)
- Isotyp:
- IgG
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Quelle:
- Rabbit
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- ELK Biotechnology
- Typ:
- Antibodies: Polyclonal Antibody