UBP18 rabbit pAb
Produktgrößen
50UL
£ POA
ES12447-50UL
100UL
£ POA
ES12447-100UL
Über dieses Produkt
- SKU:
- ES12447
- Anwendung:
- Western Blot
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- The protein encoded by this gene belongs to the ubiquitin-specific proteases (UBP) family of enzymes that cleave ubiquitin from ubiquitinated protein substrates. It is highly expressed in liver and thymus; and is localized to the nucleus. This protein efficiently cleaves only ISG15 (a ubiquitin-like protein) fusions; and deletion of this gene in mice results in a massive increase of ISG15 conjugates in tissues; indicating that this protein is a major ISG15-specific protease. Mice lacking this gene are also hypersensitive to interferon; suggesting a function of this protein in downregulating interferon responses; independent of its isopeptidase activity towards ISG15. [provided by RefSeq; Sep 2011];
- Immunogen:
- Synthesized peptide derived from human UBP18 AA range: 66-116
- Isotyp:
- IgG
- Reaktivitäten:
- Human, Mouse
- Versandbedingungen:
- Blue Ice
- Quelle:
- Rabbit
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- ELK Biotechnology
- Typ:
- Antibodies: Polyclonal Antibody
