ZBT7A rabbit pAb
Produktgrößen
50UL
£ POA
ES11928-50UL
100UL
£ POA
ES11928-100UL
Über dieses Produkt
- SKU:
- ES11928
- Anwendung:
- Western Blot, ELISA
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- function:Plays a key role in the instruction of early lymphoid progenitors to develop into B lineage by repressing T-cell instructive Notch signals (By similarity). Specifically represses the transcription of the CDKN2A gene. Efficiently abrogates E2F1-dependent CDKN2A transactivation/de-repression. Binds to the consensus sequence 5'-[GA][CA]GACCCCCCCCC-3'.;similarity:Contains 1 BTB (POZ) domain.;similarity:Contains 4 C2H2-type zinc fingers.;subunit:Interacts with BCL6.;tissue specificity:Widely expressed. In normal thymus; expressed in medullary epithelial cells and Hassle's corpuscles (at protein level). In tonsil; expressed in squamous epithelium and germinal center lymphocytes (at protein level). Up-regulated in a subset of lymphomas; as well as in a subset of breast; lung; colon; prostate and bladder carcinomas (at protein level).;
- Immunogen:
- Synthesized peptide derived from part region of human protein
- Isotyp:
- IgG
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Quelle:
- Rabbit
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- ELK Biotechnology
- Typ:
- Antibodies: Polyclonal Antibody