TNKS2 rabbit pAb
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50UL
£ POA
ES11342-50UL
100UL
£ POA
ES11342-100UL
Über dieses Produkt
- SKU:
- ES11342
- Anwendung:
- Western Blot, ELISA
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- catalytic activity:NAD(+) + (ADP-D-ribosyl)(n)-acceptor = nicotinamide + (ADP-D-ribosyl)(n+1)-acceptor.;function:May regulate vesicle trafficking and modulate the subcellular distribution of SLC2A4/GLUT4-vesicles. Has PARP activity and can modify TRF1; and thereby contribute to the regulation of telomere length.;PTM:ADP-ribosylated (-auto).;similarity:Contains 1 PARP catalytic domain.;similarity:Contains 1 SAM (sterile alpha motif) domain.;similarity:Contains 15 ANK repeats.;subcellular location:Associated with the Golgi and with juxtanuclear SLC2A4/GLUT4-vesicles. Also found around the pericentriolar matrix of mitotic centromeres. During interphase; a small fraction of TNKS2 is found in the nucleus; associated with TRF1.;subunit:Oligomerizes and associates with TNKS. Interacts with the cytoplasmic domain of LNPEP/Otase in SLC2A4/GLUT4-vesicles. Binds to the N-terminus of Grb14 and TRF1 with its ankyrin repeat region.;tissue specificity:Highly expressed in placenta; skeletal muscle; liver; brain; kidney; heart; thymus; spinal cord; lung; peripheral blood leukocytes; pancreas; lymph nodes; spleen; prostate; testis; ovary; small intestine; colon; mammary gland; breast and breast carcinoma; and in common-type meningioma. Highly expressed in fetal liver; heart and brain.;
- Immunogen:
- Synthesized peptide derived from human protein . at AA range: 950-1030
- Isotyp:
- IgG
- Reaktivitäten:
- Human, Mouse
- Versandbedingungen:
- Blue Ice
- Quelle:
- Rabbit
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- ELK Biotechnology
- Typ:
- Antibodies: Polyclonal Antibody