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Antikörper

HBEGF rabbit pAb

Produktgrößen
50UL
£ POA
ES11256-50UL
100UL
£ POA
ES11256-100UL
Über dieses Produkt
SKU:
ES11256
Anwendung:
Western Blot, ELISA
Klonalität:
Polyclonal
Konzentration:
1 mg/ml
Weitere Details:
function:May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts and smooth muscle but not endothelial cells. It is able to bind EGF receptors with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. Also acts as a diphtheria toxin receptor.;PTM:O-linked glycan attachment sites were determined by Edman degradation; O-glycanase digest suggests mucin-type glycosylation (done in HB-EGF purified from histiocytic lymphoma cell line U-937).;PTM:Several N-termini have been identified by direct sequencing. The forms with N-termini 63; 73 and 74 have been tested and found to be biologically active.;similarity:Contains 1 EGF-like domain.;subcellular location:Mature HB-EGF is released into the extracellular space and probably binds to a receptor.;
Immunogen:
Synthesized peptide derived from human protein . at AA range: 130-210
Isotyp:
IgG
Reaktivitäten:
Human, Rat, Mouse
Versandbedingungen:
Blue Ice
Quelle:
Rabbit
Lagerbedingungen:
-20[o]C
Hersteller:
ELK Biotechnology
Typ:
Antibodies: Polyclonal Antibody
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