CO5 rabbit pAb
Produktgrößen
50UL
£ POA
ES11173-50UL
100UL
£ POA
ES11173-100UL
Über dieses Produkt
- SKU:
- ES11173
- Anwendung:
- Western Blot, ELISA
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- This gene encodes a component of the complement system; a part of the innate immune system that plays an important role in inflammation; host homeostasis; and host defense against pathogens. The encoded preproprotein is proteolytically processed to generate multiple protein products; including the C5 alpha chain; C5 beta chain; C5a anaphylatoxin and C5b. The C5 protein is comprised of the C5 alpha and beta chains; which are linked by a disulfide bridge. Cleavage of the alpha chain by a convertase enzyme results in the formation of the C5a anaphylatoxin; which possesses potent spasmogenic and chemotactic activity; and the C5b macromolecular cleavage product; a subunit of the membrane attack complex (MAC). Mutations in this gene cause complement component 5 deficiency; a disease characterized by recurrent bacterial infections. Alternative splicing results in multiple transcript variants. [provided by RefSeq;
- Immunogen:
- Synthesized peptide derived from human protein . at AA range: 690-770
- Isotyp:
- IgG
- Reaktivitäten:
- Human, Rat, Mouse
- Versandbedingungen:
- Blue Ice
- Quelle:
- Rabbit
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- ELK Biotechnology
- Typ:
- Antibodies: Polyclonal Antibody