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Antikörper

IL21R rabbit pAb

Produktgrößen
50UL
£ POA
ES10875-50UL
100UL
£ POA
ES10875-100UL
Über dieses Produkt
SKU:
ES10875
Anwendung:
Western Blot, ELISA
Klonalität:
Polyclonal
Konzentration:
1 mg/ml
Weitere Details:
The protein encoded by this gene is a cytokine receptor for interleukin 21 (IL21). It belongs to the type I cytokine receptors; and has been shown to form a heterodimeric receptor complex with the common gamma-chain; a receptor subunit also shared by the receptors for interleukin 2; 4; 7; 9; and 15. This receptor transduces the growth promoting signal of IL21; and is important for the proliferation and differentiation of T cells; B cells; and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules; including JAK1; JAK3; STAT1; and STAT3. Knockout studies of a similar gene in mouse suggest a role for this gene in regulating immunoglobulin production. Three alternatively spliced transcript variants have been described. [provided by RefSeq; Jul 2010];
Immunogen:
Synthesized peptide derived from part region of human protein
Isotyp:
IgG
Reaktivitäten:
Human, Mouse
Versandbedingungen:
Blue Ice
Quelle:
Rabbit
Lagerbedingungen:
-20[o]C
Hersteller:
ELK Biotechnology
Typ:
Antibodies: Polyclonal Antibody
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