MUL1 rabbit pAb
Produktgrößen
50UL
£ POA
ES10762-50UL
100UL
£ POA
ES10762-100UL
Über dieses Produkt
- SKU:
- ES10762
- Anwendung:
- Western Blot, ELISA
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- domain:The zinc finger domain is required for E3 ligase activity.;function:E3 ubiquitin-protein ligase that plays a role in the control of mitochondrial morphology. Promotes mitochondrial fragmentation and influences mitochondrial localization. Inhibits cell growth. When overexpressed; activates JNK through MAP3K7/TAK1 and induces caspase-dependent apoptosis. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.;pathway:Protein modification; protein ubiquitination.;similarity:Contains 1 RING-type zinc finger.;subcellular location:Transported in mitochondrion-derived vesicles from the mitochondrion to the peroxisome.;subunit:Homooligomer. Interacts with MAP3K7/TAK1.;tissue specificity:Widely expressed with highest levels in the heart; skeletal muscle; placenta; kidney and liver. Barely detectable in colon and thymus.;
- Immunogen:
- Synthesized peptide derived from part region of human protein
- Isotyp:
- IgG
- Reaktivitäten:
- Human, Mouse
- Versandbedingungen:
- Blue Ice
- Quelle:
- Rabbit
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- ELK Biotechnology
- Typ:
- Antibodies: Polyclonal Antibody
