KDM3B rabbit pAb
Produktgrößen
50UL
£ POA
ES10593-50UL
100UL
£ POA
ES10593-100UL
Über dieses Produkt
- SKU:
- ES10593
- Anwendung:
- Western Blot, ELISA
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- cofactor:Binds 1 Fe(2+) ion per subunit.;domain:Leu-Xaa-Xaa-Leu-Leu (LXXLL) motifs are known to mediate the association with nuclear receptors.;function:Histone demethylase that specifically demethylates 'Lys-9' of histone H3; thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May have tumor suppressor activity.;miscellaneous:Its gene is located in the 5q region of the genome which is deleted in del(5q) interstitial deletion; a frequent deletion found in myeloid leukemias and myelodysplasias; suggesting that it may be a good candidate for the del(5q) tumor suppressor gene.;similarity:Belongs to the JHDM2 histone demethylase family.;similarity:Contains 1 JmjC domain.;tissue specificity:Ubiquitous. Highly expressed in placenta; skeletal muscle; kidney; heart and liver.;
- Immunogen:
- Synthesized peptide derived from human protein . at AA range: 230-310
- Isotyp:
- IgG
- Reaktivitäten:
- Human, Mouse
- Versandbedingungen:
- Blue Ice
- Quelle:
- Rabbit
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- ELK Biotechnology
- Typ:
- Antibodies: Polyclonal Antibody