Cleaved-Factor VII LC (R212) rabbit pAb
Produktgrößen
50UL
£ POA
ES1058-50UL
100UL
£ POA
ES1058-100UL
Über dieses Produkt
- SKU:
- ES1058
- Zusätzliche Namen:
- F7; Coagulation factor VII; Proconvertin; Serum prothrombin conversion accelerator; SPCA; Eptacog alfa
- Anwendung:
- Western Blot, Immunohistochemistry, Immunofluorescence, ELISA
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- This gene encodes coagulation factor VII which is a vitamin K-dependent factor essential for hemostasis. This factor circulates in the blood in a zymogen form; and is converted to an active form by either factor IXa; factor Xa; factor XIIa; or thrombin by minor proteolysis. Upon activation of the factor VII; a heavy chain containing a catalytic domain and a light chain containing 2 EGF-like domains are generated; and two chains are held together by a disulfide bond. In the presence of factor III and calcium ions; the activated factor then further activates the coagulation cascade by converting factor IX to factor IXa and/or factor X to factor Xa. Defects in this gene can cause coagulopathy. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing to generate mature polypeptides. [provided by RefSeq; Aug 2015];
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human FA7. AA range:171-220
- Isotyp:
- IgG
- Reaktivitäten:
- Human, Rat, Mouse
- Versandbedingungen:
- Blue Ice
- Quelle:
- Rabbit
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- ELK Biotechnology
- Typ:
- Antibodies: Polyclonal Antibody
