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Antikörper

UTRO rabbit pAb

Produktgrößen
50UL
£ POA
ES10452-50UL
100UL
£ POA
ES10452-100UL
Über dieses Produkt
SKU:
ES10452
Anwendung:
Immunohistochemistry, Immunofluorescence
Klonalität:
Polyclonal
Konzentration:
1 mg/ml
Weitere Details:
This gene shares both structural and functional similarities with the dystrophin gene. It contains an actin-binding N-terminus; a triple coiled-coil repeat central region; and a C-terminus that consists of protein-protein interaction motifs which interact with dystroglycan protein components. The protein encoded by this gene is located at the neuromuscular synapse and myotendinous junctions; where it participates in post-synaptic membrane maintenance and acetylcholine receptor clustering. Mouse studies suggest that this gene may serve as a functional substitute for the dystrophin gene and therefore; may serve as a potential therapeutic alternative to muscular dystrophy which is caused by mutations in the dystrophin gene. Alternative splicing of the utrophin gene has been described; however; the full-length nature of these variants has not yet been determined. [provided by RefSeq; Jul 2008];
Immunogen:
Synthesized peptide derived from part region of human protein
Isotyp:
IgG
Reaktivitäten:
Human, Rat, Mouse
Versandbedingungen:
Blue Ice
Quelle:
Rabbit
Lagerbedingungen:
-20[o]C
Hersteller:
ELK Biotechnology
Typ:
Antibodies: Polyclonal Antibody
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