Biotinylated Human CLDN18.2 (N-6His; C-Avi)V2
Produktgrößen
100ug
£ POA
EPT259-100UG
Über dieses Produkt
- SKU:
- EPT259
- Zusätzliche Namen:
- Claudin-18; CLDN18
- Weitere Details:
- Claudin-18(CLDN18) is a protein that in humans is encoded by the CLDN18 gene. It belongs to the group of claudins. CLDN18 belongs to the large claudin family of proteins; which form tight junction strands in epithelial cells. CLDN18 plays a major role in tight junction-specific obliteration of the intercellular space; through calcium-independent cell-adhesion activity. CLDN18 has two isoform A1 and isoform A2. IMAB362 (Claudiximab) is a monoclonal antibody against isoform 2 of Claudin-18. It is under investigation for the treatment of gastrointestinal adenocarcinomas and pancreatic tumors. IMAB362 was developed by Ganymed Pharmaceuticals AG.
- Molekulargewicht:
- 12.6 KDa
- Reinheit:
- Greater than 95% as determined by reducing SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at ≤-70[o]C; stable for 6 months after receipt. Store at ≤-70[o]C; stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.
- Hersteller:
- ELK Biotechnology
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Conjugated Protein
- Endotoxin Level:
- Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.