Recombinant Mouse IL-23
Produktgrößen
10ug
£ POA
EPT183-10UG
Über dieses Produkt
- SKU:
- EPT183
- Zusätzliche Namen:
- SGRF; IL-23p19; CLMF p40; IL-12 subunit p40; NKSF2
- Weitere Details:
- Interleukin 23 (IL-23) is a heterodimeric cytokine composed of two disulfide-linked subunits; a p19 subunit that is unique to IL-23; and a p40 subunit that is shared with IL-12. The p19 subunit has homology to the p35 subunit of IL-12; as well as to other single chain cytokines such as IL-6 and IL-11. The p40 subunit is homologous to the extracellular domains of the hematopoietic cytokine receptors. Although p19 is expressed by activated macrophages; dendritic cells; T cells; and endothelial cells; only activated macrophages and dendritic cells express p40 concurrently to produce IL-23. IL-23 has biological activities that are similar to; but distinct from IL-12. Both IL-12 and IL-23 induce proliferation and IFN-gamma production by human T cells. While IL-12 acts on both naive and memory human T cells; the effects of IL-23 is restricted to memory T cells.
- Molekulargewicht:
- 19.7&35.8 KDa
- Reinheit:
- Greater than 95% as determined by reducing SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Lyophilized protein should be stored at < -20[o]C; though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7[o]C for 2-7 days. Aliquots of reconstituted samples are stable at < -20[o]C for 3 months.
- Hersteller:
- ELK Biotechnology
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Endotoxin Level:
- Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.