Recombinant Human Sting (N-Sumo-6His)
Produktgrößen
50ug
£ POA
EPT179-50UG
Über dieses Produkt
- SKU:
- EPT179
- Zusätzliche Namen:
- Stimulator of interferon genes protein;TMEM173;Mediator of IRF3 activation;sting;
- Weitere Details:
- Stimulator of Interferon Gene(Sting;TMEM173) belongs to the TMEM173 family. STING is 379 amino acids (aa) in length. It contains an N-terminal cytoplasmic region (aa 1-20); four transmembrane segments (aa 21-173); and a C-terminal cytoplasmic domain (aa 174-379). It ubiquitously expressed in skin endothelial cells; alveolar type 2 pneumocytes; bronchial epithelium and alveolar macrophagesand. Its subunit structure associated with the MHC-II complex and Interacts with DDX58/RIG-I; MAVS and SSR2; RNF5 and TRIM56 along with TBK1. This type of protein often uses as facilitator of innate immune signaling that acts as a sensor of cytosolic DNA from bacteria and viruses and promotes the production of type I interferon.
- Molekulargewicht:
- 33.8 KDa
- Reinheit:
- Greater than 95% as determined by reducing SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at ≤-70[o]C; stable for 6 months after receipt. Store at ≤-70[o]C; stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.
- Hersteller:
- ELK Biotechnology
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Endotoxin Level:
- Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.