Recombinant Rat VEGF 164
Produktgrößen
10ug
£ POA
EPT063-10UG
Über dieses Produkt
- SKU:
- EPT063
- Zusätzliche Namen:
- Vascular endothelial growth factor A; Vascular permeability factor; VEGF; VEGF-A; VPF
- Weitere Details:
- Vascular endothelial growth factor (VEGF/VEGF-A ) is originally known as vascular permeability factor (VPF). It belongs to the PDGF family with a cysteine-knot structure comprised of eight conserved cysteine residues; and reckoned as a potent mediator in the process of angiogenesis and vasculogenesis in either fetus or adult. VEGF is particularly expressed in supraoptic ; paraventricular nuclei and the choroid plexus of the pituitary; and abundant in the corpus luteum of the ovary and in kidney glomeruli. The rat VEGF protein contains a putative 20 amino acids (aa) signal peptide; and alternative splicing of rat VEGF gene produces isoforms of 120; 144; 164 and 188 aa. Rat VEGF164 respectively displays 97% and 88% aa identity with that regions of mouse and human VEGF. VEGF can bind to the FLT1/VEGFR1 and KDR/VEGFR2 receptors; heparan sulfate and heparin; and play important roles in inducing endothelial cell proliferation; promoting cell migration; inhibiting apoptosis and inducing permeabilization of blood vessels.
- Molekulargewicht:
- 19.2 KDa
- Reinheit:
- Greater than 95% as determined by reducing SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Lyophilized protein should be stored at < -20[o]C; though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7[o]C for 2-7 days. Aliquots of reconstituted samples are stable at < -20[o]C for 3 months.
- Hersteller:
- ELK Biotechnology
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Endotoxin Level:
- Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.