Acetyl NF kB P65（K314/K315) (5G11) Mouse mAb
Produktgrößen
50UL
£ POA
EM1377-50UL
100UL
£ POA
EM1377-100UL
Über dieses Produkt
- SKU:
- EM1377
- Zusätzliche Namen:
- NF kappa B p65; NFKB3; p65; p65 NF kB; RELA; TF65; Transcription Factor p65
- Anwendung:
- Immunohistochemistry
- Klonalität:
- Monoclonal
- Konzentration:
- 1mg/mL
- Weitere Details:
- NFkB p65 is ubiquitinated leading to its proteosomal degradation; which is required for termination of the NFkB response. Phosphorylation of NFkB p65 on S536 stimulates acetylation of K310 by CBP; enhancing transcriptional activity. NFkB p65 is also acetylated at K122; enhancing DNA binding and impairing the interaction with NFKBIA. The protein is deacetylated by HDAC3. Invasion of a host by a pathogen is frequently associated with the activation of NF-kB; which coordinates various aspects of immune function required for resistance to infection.
- Immunogen:
- Synthetic Peptide
- Isotyp:
- IgG1
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Quelle:
- Mouse
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- ELK Biotechnology
- Typ:
- Antibodies: Monoclonal Antibody
