QuicKey Pro Mouse VCAM-1/CD106 (Vascular cell adhesion molecule 1) ELISA Kit
Produktgrößen
24 tests
£134,00
E-OSEL-M0030-24TESTS
48 tests
£321,00
E-OSEL-M0030-48TESTS
96 tests
£388,00
E-OSEL-M0030-96TESTS
Über dieses Produkt
- SKU:
- E-OSEL-M0030
- Zusätzliche Namen:
- VCAM1,CD106,INCAM-100,vascular cell adhesion molecule 1
- Anwendung:
- ELISA
- Weitere Details:
- Vascular cell adhesion molecule-1 (VCAM-1, CD106) is a type I membrane glycoprotein of the immunoglobulin superfamily. Mouse VCAM-1 has two isoforms: a 110 kDa transmembrane long isoform and a 45 kDa GPI-anchored short isoform, both releasable as soluble VCAM-1. VCAM-1 is induced on vascular endothelium by inflammatory stimuli and constitutively expressed on non-vascular cells including dendritic cells, macrophages, fibroblasts, bone marrow stromal cells, and others. It mediates cell adhesion and signal transduction by binding to ligands such as integrin A Alpha4B Beta1, A Alpha4B Beta7, A AlphaDB Beta2, and A Alpha9B Beta1. VCAM-1 is critical for leukocyte recruitment to inflammation sites, T/B cell development, hematopoietic progenitor cell homing, and may facilitate melanoma metastasis. Soluble VCAM-1 promotes angiogenesis and chemotaxis. It is also associated with pathological conditions like atherosclerosis, rheumatoid arthritis, systemic lupus erythematosus, inflammatory bowel disease, and allograft rejection.
- Format:
- Colorimetric method,ELISA,Sandwich
- Physischer Zustand:
- Other Biological Fluid, Plasma, Serum
- Reichweite:
- 78.13-5000 pg/mL
- Reaktivitäten:
- Mouse
- Empfindlichkeit:
- 46.88 pg/mL
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- 2-8[o]C
- Hersteller:
- Elabscience
- Typ:
- Assay Kits: ELISAs
- Datenblatt des Herstellers:cd106_(vascular_cell_adhesion_molecule_1)_elisa_kit-e_osel_m0030