QuicKey Pro Human BCAM (Basal Cell Adhesion Molecule) ELISA Kit
Produktgrößen
24 tests
£143,00
E-OSEL-H0083-24TESTS
48 tests
£307,00
E-OSEL-H0083-48TESTS
96 tests
£371,00
E-OSEL-H0083-96TESTS
Über dieses Produkt
- SKU:
- E-OSEL-H0083
- Zusätzliche Namen:
- CD239,BCAM,AU,LU,MSK19,Lutheran Blood Group Glycoprotein,Auberger B antigen,B-CAM cell surface glycoprotein
- Anwendung:
- ELISA
- Weitere Details:
- Basal-Cell Adhesion Molecule (BCAM) and Lutheran blood group glycoprotein (LU) are two alternatively spliced variants of a single immunoglobulin superfamily (IgSF) protein that differ in the length of their cytoplasmic tails. BCAM cDNA encodes a 628 amino acid (aa) residues precursor protein with a putative 31 aa signal peptide, a 597 aa extracellular domain containing three C2 type and two V-type Ig-like domains, a 21 aa transmembrane domain, and a 19 aa cytoplasmic domain. Compared to the 40 aa cytoplasmic domain present in LU, the BCAM cytoplasmic tail lacks the putative Src homology 3 (SH3) binding site that may be involved in mediating intracellular signaling. BCAM/LU has wide tissue distribution and is expressed on erythrocytes, the endothelium of blood vessels and on the basal layer of cells in the epithelia. The expression of BCAM/LU in normal tissues is higher in fetal versus adult tissues. BCAM/LU expression is also upregulated in sickle cell disease red blood cells, in activated keratinocytes and following malignant transformation in some cell types in vivo and in vitro. BCAM/LU has been shown to be an adhesion molecule that binds laminin, a basement membrane protein involved in cell differentiation, adhesion, migration and proliferation.
- Format:
- Colorimetric method,ELISA,Sandwich
- Physischer Zustand:
- Other Biological Fluid, Plasma, Serum
- Reichweite:
- 0.16-10 ng/mL
- Reaktivitäten:
- Human
- Empfindlichkeit:
- 0.09 ng/mL
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- 2-8[o]C
- Hersteller:
- Elabscience
- Typ:
- Assay Kits: ELISAs
- Datenblatt des Herstellers:p-quickey_pro_human_bcam_(basal_cell_adhesion_molecule)_elisa_kit-e_osel_h0083