Mini Sample Mouse TFPI (Tissue Factor Pathway Inhibitor) ELISA Kit
Produktgrößen
24 tests
£134,00
E-MSEL-M0127-24TESTS
48 tests
£328,00
E-MSEL-M0127-48TESTS
96 tests
£397,00
E-MSEL-M0127-96TESTS
Über dieses Produkt
- SKU:
- E-MSEL-M0127
- Zusätzliche Namen:
- Tfpi,EPI,LACI,lipoprotein-associated coagulation
- Anwendung:
- ELISA
- Weitere Details:
- Tissue Factor Pathway Inhibitor (TFPI), also called extrinsic pathway inhibitor (EPI) and lipoprotein-associated coagulation inhibitor (LACI), is a key Kunitz-type serine protease inhibitor regulating the extrinsic blood coagulation pathway. It directly inhibits factor X (Xa) and, in an Xa-dependent way, inhibits VIIa/tissue factor (TF) activity by forming a quaternary Xa/LACI/VIIa/TF complex, playing a vital antithrombotic role.TFPI is mainly produced by vascular endothelial cells, it is also expressed by vascular smooth muscle cells, megakaryocytes/platelets, monocytes and other cells, and detected in macrophages and T cells in atherosclerotic lesions. Its structure has three tandem Kunitz domains (K1, K2, K3) and a basic C-terminal region: K2 inhibits FXa's active site, while K1 inhibits FVIIa's to block the TF-FVIIa complex's procoagulant activity.
- Format:
- Colorimetric method,ELISA,Sandwich
- Physischer Zustand:
- Other Biological Fluid, Plasma, Serum
- Reichweite:
- 31.25-2000 pg/mL
- Reaktivitäten:
- Mouse
- Empfindlichkeit:
- 18.75 pg/mL
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- 2-8[o]C
- Hersteller:
- Elabscience
- Typ:
- Assay Kits: ELISAs
- Datenblatt des Herstellers:p-mini_sample_mouse_tfpi_(tissue_factor_pathway_inhibitor)_elisa_kit-e_msel_m0127