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Antikörper

Mouse RANK KappaL Antibody Pair Set

Produktgrößen
1 set
£882,00
E-KAB-0571-1SET
Über dieses Produkt
SKU:
E-KAB-0571
Zusätzliche Namen:
TNFSF11,TRANCE,RANKL,CD254,ODF,OPGL,OPTB2,hRANKL2,sOdf
Anwendung:
ELISA
Buffer:
PBS with 0.04% Proclin 300, 50% glycerol, pH 7.5, PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.5
Weitere Details:
Cytokine that binds to TNFRSF11B/OPG and to TNFRSF11A/RANK. Osteoclast differentiation and activation factor.Augments the ability of dendritic cells to stimulate naive T-cell proliferation. May be an important regulator of interactions between T-cells and dendritic cells and may play a role in the regulation of the T-cell-dependent immune response. May also play an important role in enhanced bone-resorption in humoral hypercalcemia of malignancy.Induces osteoclastogenesis by activating multiple signaling pathways in osteoclast precursor cells , chief among which is induction of long lasting oscillations in the intracellular concentration of Ca 2+ resulting in the activation of NFATC1 , which translocates to the nucleus and induces osteoclast-specific gene transcription to allow differentiation of osteoclasts.
Format:
Colorimetric method;ELISA;Sandwich
Formulierung:
PBS with 0.04% Proclin 300, 50% glycerol, pH 7.5, PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.5
Immunogen:
RANκL
Physischer Zustand:
Other Biological Fluid, Plasma, Serum
Reaktivitäten:
Mouse
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Typ:
Antibody: Antibody Pair