Human HBEGF Antibody Pair Set
Produktgrößen
1 set
£512,00
E-KAB-0428-1SET
Über dieses Produkt
- SKU:
- E-KAB-0428
- Zusätzliche Namen:
- DTR,DTS,DTSF,Diphtheria Toxin Receptor,Diphtheria toxin receptor,HB-EGF,HEGFL,Proheparin-binding EGF-like growth factor
- Anwendung:
- ELISA
- Buffer:
- PBS with 0.04% Proclin 300, 50% glycerol, pH 7.5, PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.5
- Weitere Details:
- Heparin-binding EGF-like growth factor ( HB-EGF ) is a 12-16 kDa member of the epidermal growth factor ( EGF ) family. It possesses an EGF-like domain , and a heparin-binding motif. Mature HB-EGF is a soluble peptide thatarises from proteolytic processing of the transmembrane form. Human HB -EGF shows 76% and 73% aasequence identity with rat and mouse HB-EGF , respectively. It is required for normal cardiac valve formationand normal heart function , promotes smooth muscle cell proliferation. It may be involved in macrophage-mediated cellular proliferation , it is mitogenic for fibroblasts , but not endothelial cells. HB-EGF classified as agroup 2 ErbB ligand based on its ability to activate both the EGF/ErbB1 and ErbB4 receptors. Activityassociated with ErbB4 binding appears to be limited to non -mitogenic actions , while EGFR binding inducesboth mitogenic and non-mitogenic activity.
- Format:
- Colorimetric method;ELISA;Sandwich
- Formulierung:
- PBS with 0.04% Proclin 300, 50% glycerol, pH 7.5, PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.5
- Immunogen:
- HBEGF
- Physischer Zustand:
- Other Biological Fluid, Plasma, Serum
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Antibody Pair
- Datenblatt des Herstellers:p-human_hbegf_antibody_pair_set-e_kab_0428