Mouse IL-17C (Interleukin 17C) ELISA Kit
Produktgrößen
24 tests
£134,00
E-EL-M3131-24TESTS
48 tests
£311,00
E-EL-M3131-48TESTS
96 tests
£377,00
E-EL-M3131-96TESTS
Über dieses Produkt
- SKU:
- E-EL-M3131
- Zusätzliche Namen:
- Interleukin-17C,Il-17c,Cytokine CX2
- Anwendung:
- ELISA
- Weitere Details:
- IL-17C(Interleukin 17C) is a pro-inflammatory cytokine that plays a crucial role in epithelial innate immunity, especially against intestinal bacterial pathogens, acting in an autocrine manner. It stimulates the production of antibacterial peptides and pro-inflammatory molecules for host defense via activating the NFKB and MAPK signaling pathways. It acts synergistically with IL22, TNF and IL1B to induce antibacterial peptides. It may exert a protective effect by maintaining epithelial homeostasis after inflammatory challenges, such as intestinal inflammation in a dextran sulfate sodium-induced colitis model. It can also promote an inflammatory phenotype, e.g., in psoriatic skin. Enhanced IL17C/IL17RE signaling may increase susceptibility to autoimmune diseases like autoimmune encephalitis.
- Format:
- Colorimetric method,ELISA,Sandwich
- Physischer Zustand:
- Other Biological Fluid, Plasma, Serum
- Reichweite:
- 15.63-1000 pg/mL
- Reaktivitäten:
- Mouse
- Empfindlichkeit:
- 9.38 pg/mL
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- 2-8[o]C
- Hersteller:
- Elabscience
- Typ:
- Assay Kits: ELISAs
- Datenblatt des Herstellers:p-mouse_il_17c_(interleukin_17c)_elisa_kit-e_el_m3131