Mouse ACE2 (Angiotensin I Converting Enzyme 2) ELISA Kit
Produktgrößen
24 tests
£143,00
E-EL-M3113-24TESTS
48 tests
£295,00
E-EL-M3113-48TESTS
96 tests
£356,00
E-EL-M3113-96TESTS
Über dieses Produkt
- SKU:
- E-EL-M3113
- Zusätzliche Namen:
- ACEH,ACEII
- Anwendung:
- ELISA
- Weitere Details:
- ACE2 is a member of the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases. It catalyzes the cleavage of the decapeptide angiotensin I into angiotensin-(1-9) and angiotensin II (potent vasoconstrictor) into the vasodilator angiotensin-(1-7). ACE2 is a type I membrane protein that functions as a carboxypeptidase. It cleaves between a proline and a single hydrophobic/basic residue from the COOH-terminus of its substrates. ACE2 is a zinc metalloprotease with considerable homology to angiotensin I-converting enzyme (ACE),both enzymes contain the typical HEXXH zinc-binding motif,ACE has two catalytic sites and ACE2 has only one,and ACE2 is not inhibited by ACE inhibitors captopril,lisinopril,and enalaprilat. Studies in mice showed that disruption of ACE2 induced a severe cardiac contractility defect and increased angiotensin II levels in heart. Human ACE2 has been identified as the receptor for SARS (severe acute respiratory syndrome)-coronavirus.
- Format:
- Colorimetric method,ELISA,Sandwich
- Physischer Zustand:
- Other Biological Fluid, Plasma, Serum
- Reichweite:
- 0.78-50 ng/mL
- Reaktivitäten:
- Mouse
- Empfindlichkeit:
- 0.47 ng/mL
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- 2-8[o]C
- Hersteller:
- Elabscience
- Typ:
- Assay Kits: ELISAs
- Datenblatt des Herstellers:p-mouse_ace2_(angiotensin_i_converting_enzyme_2)_elisa_kit-e_el_m3113