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Antikörper

Purified Anti-Human CD13 Antibody[WM15], Functional Grade

Produktgrößen
100 ug
£112,00
E-AB-F13860-100UG
1 mg
£149,00
E-AB-F13860-1MG
5 mg
£406,00
E-AB-F13860-5MG
25 mg
£979,00
E-AB-F13860-25MG
50 mg
£1602,00
E-AB-F13860-50MG
100 mg
£2280,00
E-AB-F13860-100MG
Über dieses Produkt
SKU:
E-AB-F13860
Zusätzliche Namen:
Alanyl (membrane) aminopeptidase,Alanyl aminopeptidase,Aminopeptidase M,AMPN,AP M,AP N,CD 13,hAPN,LAP 1,Microsomal aminopeptidase,Myeloid plasma membrane glycoprotein CD13,LAP,ANPEP,APN,CD13,GP150,LAP1,P150,PEPN,Aminopeptidase N,AP-M,AP-N,CD13 antigen,CD13APN,PEPNhAPN, gp150
Anwendung:
Block/Inhibit/Neutralise, Flow Cytometry
Buffer:
Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.
translate.label.attr.clone:
WM15
Klonalität:
Monoclonal
Konzentration:
>= 1 mg/ml
Weitere Details:
Aminopeptidase N is located in the small-intestinal and renal microvillar membrane, and also in other plasma membranes. In the small intestine aminopeptidase N plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Its function in proximal tubular epithelial cells and other cell types is less clear. The large extracellular carboxyterminal domain contains a pentapeptide consensus sequence characteristic of members of the zinc-binding metalloproteinase superfamily. Sequence comparisons with known enzymes of this class showed that CD13 and aminopeptidase N are identical. The latter enzyme was thought to be involved in the metabolism of regulatory peptides by diverse cell types, including small intestinal and renal tubular epithelial cells, macrophages, granulocytes, and synaptic membranes from the CNS. Human aminopeptidase N is a receptor for one strain of human coronavirus that is an important cause of upper respiratory tract infections. Defects in this gene appear to be a cause of various types of leukemia or lymphoma. None (Azide-Free,Low Endotoxin) are perfectly suited to be used in culture or in vivo (for nonhuman studies) for functional assays blocking, neutralizing, activation or depletion where the presence of azide may damage cells or exogenous endotoxin may signal or activate cells.
Host:
Mouse
Immunogen:
Recombinant Human CD13 protein
Isotyp:
IgG1, kappa
Aufreinigung:
protein a/g purified
Reaktivitäten:
Human
Versandbedingungen:
Blue Ice
Lagerbedingungen:
2-8[o]C Avoid freeze/thaw cycles., -20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Typ:
Antibody: Monoclonal Antibody