Elab Fluor[R] 700 Anti-Human CD49d Antibody[HP1/2]
Produktgrößen
20 tests
£135,00
E-AB-F1359M1-20TESTS
100 tests
£251,00
E-AB-F1359M1-100TESTS
2 x 100 tests
£343,00
E-AB-F1359M1-2X100TESTS
Über dieses Produkt
- SKU:
- E-AB-F1359M1
- Zusätzliche Namen:
- VLA-4 A Alpha chain;A Alpha4 integrin;Integrin A Alpha4 chain;ITGA4
- Anwendung:
- Flow Cytometry
- Buffer:
- PBS
- translate.label.attr.clone:
- HP1/2
- Klonalität:
- Recombinant Monoclonal
- Konjugat:
- Elab Fluor® 700
- Weitere Details:
- CD49d is a 150 kD A Alpha integrin chain known as A Alpha4 integrin or VLA-4 A Alpha chain. It forms a heterodimer with either integrin B Beta1 (A Alpha4B Beta1, VLA-4) or B Beta7 (A Alpha4B Beta7). CD49d is expressed broadly on T lymphocytes, B lymphocytes, monocytes, thymocytes, eosinophils, basophils, mast cells, NK cells, dendritic cells, and some non-hematopoietic cells, but not on normal red blood cells, platelets or neutrophils. VLA-4 binds to VCAM-1 (CD106) and fibronectin. A Alpha4B Beta7 is the receptor for VCAM-1 and MAdCAM-1. CD49d participates in mononuclear cell trafficking to endothelial sites of inflammation and has roles in cell-cell interactions and cell adhesion to extracellular matrices. CD49d is involved in lymphocyte migration, T cell activation, and hematopoietic stem cell differentiation. CD49d is a marker to isolate pure populations of Treg cells due to its absence on Foxp3+ cells.
- Host:
- Mouse
- Immunogen:
- CD49d
- Isotyp:
- IgG2a, kappa
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- 2-8[o]C Do not freeze. Protect from light.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Recombinant Antibodies
- Datenblatt des Herstellers:2]-e_ab_f1359m1