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Antikörper

AF/LE Purified Anti-Mouse CD4 Antibody[RM4-5]

Produktgrößen
25 ug
£66,00
E-AB-F13530-25UG
100 ug
£89,00
E-AB-F13530-100UG
1 mg
£171,00
E-AB-F13530-1MG
5 mg
£490,00
E-AB-F13530-5MG
25 mg
£1515,00
E-AB-F13530-25MG
50 mg
£2247,00
E-AB-F13530-50MG
100 mg
£3211,00
E-AB-F13530-100MG
Über dieses Produkt
SKU:
E-AB-F13530
Zusätzliche Namen:
L3T;T-cell surface antigen T4/Leu;T-cell surface glycoprotein CD;L3T4;Ly-4;T4;T-cell surface antigen T4/Leu-3;T-cell surface glycoprotein CD4;Cd4; L3T4;CD4mut;p55
Anwendung:
Flow Cytometry
Buffer:
Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.
translate.label.attr.clone:
RM4-5
Klonalität:
Monoclonal
Konzentration:
>= 1 mg/ml
Weitere Details:
Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex. LCK then initiates different intracellular signaling pathways by phosphorylating various substrates ultimately leading to lymphokine production, motility, adhesion and activation of T-helper cells. In other cells such as macrophages or NK cells, plays a role in differentiation/activation, cytokine expression and cell migration in a TCR/LCK-independent pathway. Participates in the development of T-helper cells in the thymus and triggers the differentiation of monocytes into functional mature macrophages.
Host:
Rat
Immunogen:
CD4|Recombinant Mouse CD4 protein
Isotyp:
IgG2a, kappa
Reinheit:
>98%
Aufreinigung:
protein a/g purified
Reaktivitäten:
Mouse
Versandbedingungen:
Blue Ice
Lagerbedingungen:
2-8[o]C Avoid freeze/thaw cycles., -20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Typ:
Antibody: Monoclonal Antibody
  • Datenblatt des Herstellers:G0KC08