AF/LE Purified Anti-Mouse CD4 Antibody[RM4-5]
Produktgrößen
25 ug
£66,00
E-AB-F13530-25UG
100 ug
£89,00
E-AB-F13530-100UG
1 mg
£171,00
E-AB-F13530-1MG
5 mg
£490,00
E-AB-F13530-5MG
25 mg
£1515,00
E-AB-F13530-25MG
50 mg
£2247,00
E-AB-F13530-50MG
100 mg
£3211,00
E-AB-F13530-100MG
Über dieses Produkt
- SKU:
- E-AB-F13530
- Zusätzliche Namen:
- L3T;T-cell surface antigen T4/Leu;T-cell surface glycoprotein CD;L3T4;Ly-4;T4;T-cell surface antigen T4/Leu-3;T-cell surface glycoprotein CD4;Cd4; L3T4;CD4mut;p55
- Anwendung:
- Flow Cytometry
- Buffer:
- Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.
- translate.label.attr.clone:
- RM4-5
- Klonalität:
- Monoclonal
- Konzentration:
- >= 1 mg/ml
- Weitere Details:
- Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex. LCK then initiates different intracellular signaling pathways by phosphorylating various substrates ultimately leading to lymphokine production, motility, adhesion and activation of T-helper cells. In other cells such as macrophages or NK cells, plays a role in differentiation/activation, cytokine expression and cell migration in a TCR/LCK-independent pathway. Participates in the development of T-helper cells in the thymus and triggers the differentiation of monocytes into functional mature macrophages.
- Host:
- Rat
- Immunogen:
- CD4|Recombinant Mouse CD4 protein
- Isotyp:
- IgG2a, kappa
- Reinheit:
- >98%
- Aufreinigung:
- protein a/g purified
- Reaktivitäten:
- Mouse
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- 2-8[o]C Avoid freeze/thaw cycles., -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Monoclonal Antibody
- Datenblatt des Herstellers:G0KC08