APC Anti-Mouse/Rat Foxp3 Antibody[FJK-16s]
Produktgrößen
25 ug
£158,00
E-AB-F1351UE-25UG
100 ug
£282,00
E-AB-F1351UE-100UG
Über dieses Produkt
- SKU:
- E-AB-F1351UE
- Zusätzliche Namen:
- IPEXJM2ScurfinZinc finger protein JM2;Forkhead box protein P3
- Anwendung:
- Flow Cytometry
- Buffer:
- PBS
- translate.label.attr.clone:
- FJK-16s
- Klonalität:
- Monoclonal
- Konjugat:
- APC
- Konzentration:
- 0.2 mg/ml
- Weitere Details:
- FOXP3 is a 47 kD transcription factor, also known as Forkhead box protein P3, Scurfin, JM2, or IPEX. It is proposed to be a master regulatory gene and more specific marker of T regulatory cells than most cell surface markers (such as CD4 and CD25). Transduced expression of FOXP3 in CD4+/CD25- cells has been shown to induce GITR, CD103, and CTLA4 and impart a T regulatory cell phenotype. FOXP3 is mutated in X-linked autoimmunity-allergic dysregulation syndrome (XLAAD or IPEX) in humans and in "scurfy" mice. Overexpression of FOXP3 has been shown to lead to a hypoactive immune state suggesting that this transcriptional factor is a central regulator of T cell activity.
- Host:
- Rat
- Immunogen:
- Foxp3
- Isotyp:
- IgG2a, kappa
- Reaktivitäten:
- Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- 2-8[o]C Do not freeze. Protect from light.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Monoclonal Antibody
- Datenblatt des Herstellers:rat_foxp3_antibody[fjk_16s]-e_ab_f1351ue