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Antikörper

APC Anti-Mouse CD163 Antibody[S15049F]

Produktgrößen
25 ug
£128,00
E-AB-F1295UE-25UG
100 ug
£328,00
E-AB-F1295UE-100UG
Über dieses Produkt
SKU:
E-AB-F1295UE
Zusätzliche Namen:
MM130SCARI1;M130
Anwendung:
Flow Cytometry
Buffer:
PBS
translate.label.attr.clone:
S15049F
Klonalität:
Monoclonal
Konjugat:
APC
Konzentration:
0.2 mg/ml
Weitere Details:
CD163 is a member of the group B scavenger receptor cysteine-rich superfamily, also known as GHI/61, M130, RM3/1, p155, hemoglobin-haptoglobin complex receptor, or macrophage-associated antigen. It is a 134 kD (non-reduced)/155 kD (reduced) glycoprotein primarily expressed on macrophages, Kupffer cells, monocytes, a subset of dendritic cells, and a subset of hematopoietic stem/progenitor cells. CD163 binds to haptoglobin-hemoglobin complex and TWEAK, and plays a role in clearing hemoglobin and regulating cytokine production by macrophages. Membrane CD163 can be cleaved by metalloproteinases (MMP), resulting in a soluble form. Elevated serum level of sCD163 has been implicated in many kinds of inflammatory diseases.
Host:
Rat
Immunogen:
CD163
Isotyp:
IgG2a, kappa
Reaktivitäten:
Mouse
Versandbedingungen:
Blue Ice
Lagerbedingungen:
2-8[o]C Do not freeze. Protect from light.
Hersteller:
Elabscience
Typ:
Antibody: Monoclonal Antibody