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Antikörper

AF/LE Purified Anti-Mouse CD172a Antibody[P84]

Produktgrößen
25 ug
£66,00
E-AB-F12860-25UG
100 ug
£89,00
E-AB-F12860-100UG
1 mg
£171,00
E-AB-F12860-1MG
5 mg
£490,00
E-AB-F12860-5MG
25 mg
£1515,00
E-AB-F12860-25MG
50 mg
£2247,00
E-AB-F12860-50MG
100 mg
£3211,00
E-AB-F12860-100MG
Über dieses Produkt
SKU:
E-AB-F12860
Zusätzliche Namen:
Myd;SHPS;Ptpns;Bit;Myd1;Ptpns1;Shps1;Sirp;Sirpa; SIRP&beta-1-1;SIRPαSIRPβAI835480;CD172a;P84;SHP-1;SHPS-1
Anwendung:
Flow Cytometry
Buffer:
Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.
translate.label.attr.clone:
P84
Klonalität:
Monoclonal
Konzentration:
>= 1 mg/ml
Weitere Details:
Immunoglobulin-like cell surface receptor for CD47. Acts as a docking protein and induces translocation of PTPN6, PTPN11 and other binding partners from the cytosol to the plasma membrane. Supports adhesion of cerebellar neurons, neurite outgrowth and glial cell attachment. May play a key role in intracellular signaling during synaptogenesis and in synaptic function. Involved in the negative regulation of receptor tyrosine kinase-coupled cellular responses induced by cell adhesion, growth factors or insulin. Mediates negative regulation of phagocytosis, mast cell activation and dendritic cell activation. CD47 binding prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Plays a role in antiviral immunity and limits new world arenavirus infection by decreasing virus internalization. Receptor for THBS1. Interaction with THBS1 stimulates phosphorylation of SIRPA. In response to THBS1, involved in ROS signaling in non-phagocytic cells, stimulating NADPH oxidase-derived ROS production.
Host:
Rat
Immunogen:
CD172a|Recombinant Mouse CD172a protein
Isotyp:
IgG1, kappa
Reinheit:
>98%
Aufreinigung:
protein a/g purified
Reaktivitäten:
Mouse
Versandbedingungen:
Blue Ice
Lagerbedingungen:
2-8[o]C Avoid freeze/thaw cycles., -20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Typ:
Antibody: Monoclonal Antibody
  • Datenblatt des Herstellers:LR8Z5R
Human peripheral blood Granulocyte cell were stained with 0.2 ug Purified Anti-Human CD87 Antibody[10E1] (Right) and 0.2 ug Rat IgG1, K Kappa Isotype Control (Left), followed by Elab Fluor® 647-conjugated Goat Anti-Ret IgG Secondary Antibody.
Human peripheral blood lymphocytes cell were stained with 0.2 ug AF/LE Purified Anti-Human CD25 Antibody[7G7B6] (Right) and 0.2 ug Mouse IgG2a, K Kappa Isotype Control (Left), followed by Elab Fluor® 647-conjugated Goat Anti-Mouse IgG Secondary Antibody, then anti-Human CD4 PE-conjugated Monoclonal Antibody.
K562 were stained with 0.2 ug Purified Anti-Human CD49e Antibody[IIA1] (Right) and 0.2 ug Mouse IgG1, K Kappa Isotype Control (Left), followed by Elab Fluor® 647-conjugated Goat Anti-Mouse IgG Secondary Antibody.
Human peripheral blood granulocytes cell were stained with 0.2 ug Purified Anti-Human CD32 Antibody[AT10] (Right) and 0.2 ug Mouse IgG1, K Kappa Isotype Control (Left), followed by Elab Fluor® 647-conjugated Goat Anti-Mouse IgG Secondary Antibody.
Human peripheral blood Granulocyte cell were stained with 0.2 ug Purified Anti-Human CD87 Antibody[10E1] (Right) and 0.2 ug Rat IgG1, K Kappa Isotype Control (Left), followed by Elab Fluor® 647-conjugated Goat Anti-Ret IgG Secondary Antibody.