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Antikörper

APC Anti-Mouse CD51 Antibody[RMV-7]

Produktgrößen
25 ug
£106,00
E-AB-F1235UE-25UG
100 ug
£220,00
E-AB-F1235UE-100UG
Über dieses Produkt
SKU:
E-AB-F1235UE
Zusätzliche Namen:
ITGAV;Integrin alpha-V;Integrin A AlphaV chain;Vitronectin Receptor;A AlphaV integrin
Anwendung:
Flow Cytometry
Buffer:
PBS
translate.label.attr.clone:
RMV-7
Klonalität:
Monoclonal
Konjugat:
APC
Konzentration:
0.2 mg/ml
Weitere Details:
CD51 is a 140 kD protein, also known as A AlphaV integrin, vitronectin receptor, and integrin A AlphaV. It is a member of the integrin family, expressed on activated T cells, polymorphonuclear granulocytes, platelets, blastocysts, and osteoclasts. CD51 forms heterodimers by association with integrins B Beta1, B Beta3, B Beta5 or B Beta6; these complexes then act as receptors for multiple extracellular matrix proteins (ECM). The A Alphavintegrin heterodimers have varied functions in development, stimulation/activation and homeostasis. The primary ligands for CD51 complexes are fibronectin, fibrinogen, vitronectin, thrombspondin, von Willebrand factor, and CD31. The RMV-7 antibody has been reported to block binding of CD51 to vitronectin, fibronectin, and CD31 in some cell types, as well as blocking LAK cell cytotoxicity.
Host:
Rat
Immunogen:
CD51
Isotyp:
IgG1, kappa
Reaktivitäten:
Mouse
Versandbedingungen:
Blue Ice
Lagerbedingungen:
2-8[o]C Do not freeze. Protect from light.
Hersteller:
Elabscience
Typ:
Antibody: Monoclonal Antibody