APC Anti-Human CD279/PD-1 Antibody[EH12.2H7]
Produktgrößen
20 tests
£129,00
E-AB-F1229E-20TESTS
100 tests
£208,00
E-AB-F1229E-100TESTS
2 x 100 tests
£291,00
E-AB-F1229E-2X100TESTS
Über dieses Produkt
- SKU:
- E-AB-F1229E
- Zusätzliche Namen:
- PD1;PDCD1;Protein PD-1;hPD-1
- Anwendung:
- Flow Cytometry
- Buffer:
- PBS
- translate.label.attr.clone:
- EH12.2H7
- Klonalität:
- Monoclonal
- Konjugat:
- APC
- Konzentration:
- 5 ul/test
- Weitere Details:
- Programmed cell death 1 (PD-1), also known as CD279, is a 55 kD member of the immunoglobulin superfamily. CD279 contains the immunoreceptor tyrosine-based inhibitory motif (ITIM) in the cytoplasmic region and plays a key role in peripheral tolerance and autoimmune disease. CD279 is expressed predominantly on activated T cells, B cells, and myeloid cells. PD-L1 and PD-L2 are ligands of CD279 (PD-1) and are members of the B7 gene family. Evidence suggests overlapping functions for these two PD-1 ligands and their constitutive expression on some normal tissues and upregulation on activated antigen-presenting cells. Interaction of CD279 ligands results in inhibition of T cell proliferation and cytokine secretion.
- Host:
- Mouse
- Immunogen:
- CD279/PD-1
- Isotyp:
- IgG1, kappa
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- 2-8[o]C Do not freeze. Protect from light.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Monoclonal Antibody
- Datenblatt des Herstellers:pd_1_antibody[eh12.2h7]-e_ab_f1229e