APC Anti-Mouse IL-17A Antibody[TC11-18H10.1]
Produktgrößen
50 tests
£97,00
E-AB-F1199E-50TESTS
100 tests
£128,00
E-AB-F1199E-100TESTS
2 x 100 tests
£174,00
E-AB-F1199E-2X100TESTS
Über dieses Produkt
- SKU:
- E-AB-F1199E
- Zusätzliche Namen:
- CTLA-8;CTLA8;Cytotoxic T-lymphocyte-associated antigen 8;IL-17;IL-17A;Interleukin-17A
- Anwendung:
- Flow Cytometry
- Buffer:
- PBS
- translate.label.attr.clone:
- TC11-18H10.1
- Klonalität:
- Monoclonal
- Konjugat:
- APC
- Konzentration:
- 5 ul/test
- Weitere Details:
- IL-17, also known as CTLA-8, is a T cell-expressed pleiotropic cytokine that exhibits a high degree of homology to a protein encoded by the ORF13 gene of herpes virus Saimiri. IL-17 is produced by Th cells (Th17) that are distinct from the traditional Th1- and Th2-cell subsets. IL-23 plays an important role in triggering IL-17 production. Both recombinant and natural IL-17 have been shown to exist as disulfide linked homodimers. IL-17 exhibits multiple biological activities on a variety of cells including: the induction of IL-6 and IL-8 production in fibroblasts, activation of NF-K KappaB, and costimulation of T cell proliferation. IL-17 is an essential inflammatory mediator in the development of autoimmune diseases. Neutralization of IL-17 with monoclonal antibody is able to ameliorate the disease course.
- Host:
- Rat
- Immunogen:
- IL-17A
- Isotyp:
- IgG1, kappa
- Reaktivitäten:
- Mouse
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- 2-8[o]C Do not freeze. Protect from light.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Monoclonal Antibody
- Datenblatt des Herstellers:p-apc_anti_mouse_il_17a_antibody[tc11_18h10.1]-e_ab_f1199e