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Antikörper

Purified Anti-Mouse CD366/Tim-3 Antibody[RMT3-23], Functional Grade

Produktgrößen
100 ug
£89,00
E-AB-F11920-100UG
1 mg
£171,00
E-AB-F11920-1MG
5 mg
£490,00
E-AB-F11920-5MG
25 mg
£1515,00
E-AB-F11920-25MG
50 mg
£2247,00
E-AB-F11920-50MG
100 mg
£3211,00
E-AB-F11920-100MG
Über dieses Produkt
SKU:
E-AB-F11920
Zusätzliche Namen:
TIM-,Tim3,TIM-3,Timd,Timd3,T-cell membrane protein,T-cell immunoglobulin mucin receptor,T-cell immunoglobulin and mucin domain-containing protein,Tim,TIM-,Tim3,Timd,TIM-3,Timd3,HAVcr-2,Hepatitis A virus cellular receptor 2 homolog,T-cell immunoglobulin and mucin domain-containing protein 3,T-cell immunoglobulin mucin receptor 3,T-cell membrane protein 3,TIMD-3,Havcr2,T cell immunoglobulin and mucin domain containing 3 protein, hepatitis virus cellular receptor 2
Anwendung:
Block/Inhibit/Neutralise, Flow Cytometry
Buffer:
Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.
translate.label.attr.clone:
RMT3-23
Klonalität:
Monoclonal
Konzentration:
>= 1 mg/ml
Weitere Details:
CD366 (Tim-3) is a transmembrane protein also known as T cell immunoglobulin and mucin domain containing protein-3. Tim-3 is expressed at high levels on activated T cells (preferentially on Th1 cells, monocytes/macrophages, and dendritic cells). Tim-3 has also been shown to exist as a soluble protein. Cells expressing Tim-3 are present at high levels in the CNS of animals at the onset of experimental autoimmune encephalomyelitis (EAE), a disease mediated by lymphocytes secreting Th1-like cytokines. Tim-3 has been proposed to inhibit Th1-mediated immune responses and promote immunological tolerance. None (Azide-Free,Low Endotoxin) are perfectly suited to be used in culture or in vivo (for nonhuman studies) for functional assays blocking, neutralizing, activation or depletion where the presence of azide may damage cells or exogenous endotoxin may signal or activate cells.
Host:
Rat
Immunogen:
Recombinant Mouse CD366 protein
Isotyp:
IgG2a, kappa
Aufreinigung:
protein a/g purified
Reaktivitäten:
Mouse
Versandbedingungen:
Blue Ice
Lagerbedingungen:
2-8[o]C Avoid freeze/thaw cycles., -20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Typ:
Antibody: Monoclonal Antibody
HEK293T cells transfected with pcDNA3.1 plasmid encoding Mouse CD366 gene were stained with 0.2 ug Purified Anti-Mouse CD366 Antibody[RMT3-23], Functional Grade (Right) and 0.2 ug Rat IgG2a, K Kappa Isotype Control (Left), followed by APC-conjugated Goat Anti-Rat IgG Secondary Antibody.
Human peripheral blood lymphocytes cell were stained with 0.2 ug AF/LE Purified Anti-Human CD25 Antibody[7G7B6] (Right) and 0.2 ug Mouse IgG2a, K Kappa Isotype Control (Left), followed by Elab Fluor® 647-conjugated Goat Anti-Mouse IgG Secondary Antibody, then anti-Human CD4 PE-conjugated Monoclonal Antibody.
K562 were stained with 0.2 ug Purified Anti-Human CD49e Antibody[IIA1] (Right) and 0.2 ug Mouse IgG1, K Kappa Isotype Control (Left), followed by Elab Fluor® 647-conjugated Goat Anti-Mouse IgG Secondary Antibody.
Human peripheral blood granulocytes cell were stained with 0.2 ug Purified Anti-Human CD32 Antibody[AT10] (Right) and 0.2 ug Mouse IgG1, K Kappa Isotype Control (Left), followed by Elab Fluor® 647-conjugated Goat Anti-Mouse IgG Secondary Antibody.
Human peripheral blood Granulocyte cell were stained with 0.2 ug Purified Anti-Human CD87 Antibody[10E1] (Right) and 0.2 ug Rat IgG1, K Kappa Isotype Control (Left), followed by Elab Fluor® 647-conjugated Goat Anti-Ret IgG Secondary Antibody.