APC Anti-Mouse CD150/SLAM Antibody[TC15-12F12.2]
Produktgrößen
25 ug
£117,00
E-AB-F1177UE-25UG
100 ug
£259,00
E-AB-F1177UE-100UG
Über dieses Produkt
- SKU:
- E-AB-F1177UE
- Zusätzliche Namen:
- CD 150;Signaling lymphocytic activation molecule;Slam;Slamf1
- Anwendung:
- Flow Cytometry
- Buffer:
- PBS
- translate.label.attr.clone:
- TC15-12F12.2
- Klonalität:
- Monoclonal
- Konjugat:
- APC
- Konzentration:
- 0.2 mg/ml
- Weitere Details:
- CD150 is a 75-95 kD member of the immunoglobulin superfamily, also known as SLAM (signaling lymphocyte activation molecule) or IPO-3. CD150, a single chain type I transmembrane molecule, is expressed on thymocytes, T cell subsets, B cells, dendritic cells, and endothelial cells. The expression is upregulated upon activation. CD150 expression has been shown to be maintained on Th1 but not Th2 clones. T regulatory cells express a relatively high level of CD150. Antibodies against CD150 have been shown to augment IFN-G Gamma production by Th1 cells, especially when co-stimulated through the TCR. CD150 associates with the src homology 2-domain-containing protein tyrosine phosphatase SHP-2, and this association is thought to be involved in signal transduction. In combination with CD48, CD150 is a useful marker for hematopoietic stem cell studies.
- Host:
- Rat
- Immunogen:
- CD150/SLAM
- Isotyp:
- IgG2a, lambda
- Reaktivitäten:
- Mouse
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- 2-8[o]C Do not freeze. Protect from light.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Monoclonal Antibody
- Datenblatt des Herstellers:bLivH0