APC Anti-Human CD197/CCR7 Antibody[G043H7]
Produktgrößen
20 tests
£120,00
E-AB-F1159E-20TESTS
100 tests
£272,00
E-AB-F1159E-100TESTS
2 x 100 tests
£383,00
E-AB-F1159E-2X100TESTS
Über dieses Produkt
- SKU:
- E-AB-F1159E
- Zusätzliche Namen:
- EBI1EVI1;CCR-7;CDw197;CMKBR7
- Anwendung:
- Flow Cytometry
- Buffer:
- PBS
- translate.label.attr.clone:
- G043H7
- Klonalität:
- Monoclonal
- Konjugat:
- APC
- Konzentration:
- 5 ul/test
- Weitere Details:
- CCR7, also known as CD197, is a chemokine receptor that binds CCL19 and CCL21. CCR7 and its ligands link innate and adaptive immunity by affecting interactions between T cells and dendritic cells and their downstream effect. Naive T cells enter the lymph node through high endothelial venules, which express CCL21. Dendritic cells and macrophages enter the lymph node through afferent lymphatics. The encounter of T cells and dendritic cells in the T cell zone is CCR7-dependent. In addition, during immunological surveillance, B cells recirculate between B-cell-rich compartments (follicles or B cell zones) in secondary lymphoid organs, surveying for antigen. After antigen binding, B cells move to the boundary of B and T zones to interact with T-helper cells; this B cell migration is directed by CCR7 and its ligands. CCR7-positive cancer cell expression has been associated with lymph node metastasis.
- Host:
- Mouse
- Immunogen:
- CD197/CCR7
- Isotyp:
- IgG2a, kappa
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- 2-8[o]C Do not freeze. Protect from light.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Monoclonal Antibody
- Datenblatt des Herstellers:ccr7_antibody[g043h7]-e_ab_f1159e